Medicated AK Mild Lotion

Quasi-drug productLotion

Quick-absorption moisturizing lotion

Lotion made with nanoized natural ceramides to help restore barrier function and hydrate dryness-prone skin. Contains the skin-protecting ingredient Lipidure® as well as naturally derived amino acids for added moisture. Perfect for face and body.

Size: 250 mL
Other sizes are available as well. Contact us through our Request for AK samples / materials page for details.

Hypoallergenic*, contains no fragrances, dyes, mineral oil. Patch tested*
*Some users may still experience irritation

Rosette's proprietary micronization technique

Natural ceramide has outstanding benefits for the skin, but it is also a difficult ingredient to formulate due to poor solubility. At Rosette, we apply a proprietary micronization technique to boost the solubility of natural ceramide so that it penetrates uniformly throughout the stratum corneum. The fine particles are micronized using an ultra-high-pressure processing device. The uniform size also helps the ceramide absorb more readily into the skin.

Electron microscope image

Non-micronized ceramide powder
Micronized natural ceramide

The micronization process has been shown to reduce the natural ceramide particles to an average diameter of just 1/760th of their original size while also making them more uniform.

< Measurement conditions >
Imaging device: Hitachi H-7600 at 100 kV
Sample preparation: Negative staining (uranyl acetate)
Dispersion: Copper grid with 400-mesh carbon support film
Suspension/dilution: Distilled water
Images taken at the Hanaichi Ultrastructure Research Institute

Micronized ceramide solution

Left: Solution containing non-micronized natural ceramide
Right: Solution containing micronized natural ceramide

< Measurement conditions >
Each solution was applied to the surface of surgical tape in the amount of 0.05 grams and photographed

The micronized natural ceramide solution used in AK Series product showed higher transparency than the non-micronized solution, indicating better skin absorption.


Active ingredient: Glycyrrhizic acid 2K
Other ingredients: Horse sphingolipid, 2-methacryloyloxyethyl phosphorylcholine/butyl methacrylate copolymer, carrot extract, concentrated glycerin, diphosphoglycerate, diethylene glycol monoethyl ether, 06-benzylguanine, polyoxyethylene cetylether, isostearyl alcohol, glycerine ethyl hexyl ether, carboxyvinyl polymer, sodium hydroxide